“It’s the hottest, burning, high-passion piece I’ve ever heard in my life.” Brian May names the guitar solo he considers the greatest in the world

Freddie Mercury and Brian May of the band Queen at Live Aid on July 13, 1985 in London, United Kingdom.
Brian May performs with Queen at Live Aid, in London, July 13, 1985. (Image credit: FG/Bauer-Griffin/Getty Images)

Everyone has a favorite guitar solo — Brian May included.

While the Queen guitarist drew tonal inspiration from Rory Gallagher and has called Ritchie Blackmore an incendiary trailblazer of electric guitar, neither man played what he considers the greatest solo ever recorded. That honor, for May, belongs to Eric Clapton on “Key to Love,” from Blues Breakers With Eric Clapton.

“It’s the hottest, burning, high-passion piece I’ve ever heard in my life — still to this day,” May reveals (via Classic Rock). “I just love it. It totally rips, and I’ll never get over that. That’s one of my great inspirations.”

Key To Love - YouTube Key To Love - YouTube
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Clapton was just 20 when he left the Yardbirds to join John Mayall & the Bluesbreakers, a move that coincided with what Jeff Beck later described as a streak of jealousy when his former band beat him to a U.S. breakthrough. In hindsight, though, Clapton hardly needed to worry: his brief tenure with the Bluesbreakers produced one of the defining blues-rock records of the era — an album that would go on to inspire future guitar giants, including Eddie Van Halen, who credited Clapton as a primary influence.

Though “Key to Love” runs just over two minutes, its loose, swinging groove builds toward a climactic stretch where Clapton unleashes roughly 30 seconds of unrestrained lead work.

“He burned in that solo!” May gushes. “The whole track revolves around that solo. Every time I put it on, I’m just waiting.

“John Mayall’s great,” he adds, “but you’re waiting for that moment when Eric rips out, and suddenly he’s whacking into those top notes. It’s incredible. Absolutely spine-chilling.”

Brian May - Blues Breaker - YouTube Brian May - Blues Breaker - YouTube
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May and Van Halen later paid tribute to Clapton on May’s 1983 solo EP Star Fleet Project, where the pair went head-to-head on the 13-minute blues workout “Blues Breaker.” Clapton, however, said he felt “almost insulted.”

“I think he hated it,” May said with a laugh in a 2023 interview with Guitar Player. “But he’s entitled. Eric could do anything and he’ll still be our hero. There’s probably lots of things I disagree with Eric about, but that doesn’t change anything. He’s been one of the greatest inspirations of my life, and that’ll never change.”

For May, Clapton’s playing didn’t just set a standard — it raised his own. And despite any critical remarks, the mutual respect between them is clear: they’ve shared the stage on several occasions, a quiet acknowledgment that the admiration runs both ways.

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A freelance writer with a penchant for music that gets weird, Phil is a regular contributor to ProgGuitar World, and Total Guitar magazines and is especially keen on shining a light on unknown artists. Outside of the journalism realm, you can find him writing angular riffs in progressive metal band, Prognosis, in which he slings an 8-string Strandberg Boden Original, churning that low string through a variety of tunings. He's also a published author and is currently penning his debut novel which chucks fantasy, mythology and humanity into a great big melting pot.